Absolutely not. These keygens are almost always bundled with cryptocurrency miners or remote access trojans (RATs). Delete immediately and run a full antivirus scan.
If you specifically need a portable diagramming tool that can run from a USB drive without installation, consider these open-source or free alternatives: Microsoft Visio Viewer, see Visio diagrams for free download microsoft visio portable free
A legitimate portable application runs entirely from a folder or USB drive without modifying the Windows registry or leaving traces on the host machine. However, — not for Visio 2016, 2019, 2021, or Microsoft 365. Absolutely not
Cracked portable versions are frozen in time. You won’t get: If you specifically need a portable diagramming tool
Microsoft has a free, web-based version of Visio for basic diagramming. It runs entirely in your browser (Chrome, Edge, Firefox) and works on any device. This is the closest you can get to "portable" legally.
(Date: March 23, 2026)