For players utilizing the RUNE release, the game is best enjoyed as a "campaign sampler." Playing through the Reassemble story, the War for Wakanda, and the Hawkeye operations provides a satisfying, complete narrative arc. Attempting to grind the endgame gear loop is likely to result in burnout due to the repetitive nature of the level design.
Guide :: General Tips for Marvel's Avengers - Steam Community Marvels Avengers The Definitive Edition-RUNE